A STUDY TO ASCERTAIN THE ADVERSE EFFECTS OF MORPHINE IN CANCER PATIENTS BEING TREATED FOR SEVERE PAIN

Pain is a distressing symptom of cancer that affects the quality life patients, families, and caregivers. Moderate to severe pain common throughout disease trajectory cancer, its prevalence increases course illness, it has been reported in 59% patients undergoing anticancer treatment, 64% those with advanced/metastatic 33% having completed curative treatment. Adequate management cornerstone for cancer. [1] WHO guidelines on continue provide framework approach pharmacologic terms Ladder, wherein Step 1 mild prescribed NSAIDS, 2 moderate NSAIDS along synthetic opioids adjuvants step 3 strong like Morphine adjuvants. being an excellent analgesic nowadays standard care terminal pain. However, potency double edged sword can give rise side effects as well much feared adverse effects. This study was undertaken assess undesirable treated Morphine. AIM To find association morphine (by 4 point verbal rating scale) patient long term therapy. MATERIAL AND METHODS It hospital based longitudinal observational study, conducted palliative center, SMS hospital, Jaipur, after obtaining due approval from ethics committee research review board institution. DURATION OF STUDY: One year. TOTAL PATIENTS: 30 evaluated one month initiation opioid ELIGIBILITY CRITERIA: Inclusion criteria 1. Cancer visiting OPD distressing, somatic requiring treatment (step ladder). 2. Patients all ages both sexes. 3. willing informed consent 4. who understand four scale. Exclusion Criteria: deranged liver kidney functions. Patient predominantly neuropathic altered sensorium. not consent.